Please anyone let me know if there is a class action law suit or where we can start one? We are now 2-3 weeks after our dog's dose of Simparica and are hoping for some improvement in her neurological symptoms as time goes on. He has been drinking more water then usual. I have been feeding her some white rice hoping it improves. He seems sometimes anxious and is sensitive to noise outside. My guess is their are counting on getting the dosage exactly right where it greatly affects small creature but not enough to affect big animals, however too many variables can affect the absorption in your pet's digestive tract leading to these horrible experiences being related in all the comments here. old . She does have history of seizures. He had no events and seemed to be a healthy and happy animal. Was checking out before using . I feel like the simperica trio has somehow affected his Pituitary/Andrenal glands are maybe even acting as blockers to them. Hope your pup is doing better!! Note: Lotilaner (Credelio) AE reports were not available via FOIA due to the newness of this drug Spinosad (Comfortis) AE reports not available at time of analysis If your dog has reactions to this medicine, push fluids! But I noticed that I had to "wake him' several times in only 2 minutes time, but he wasn't sleeping, his eyes were open and I saw them rolling in the back of his head! Our pup only made it 4 months after her first seizure, but this did seem to help her symptoms toward the end. Im going to keep a close watch on him over the next few days. I have a completely different dog. Contact your vet if your dog misses a month or more of heartworm preventionyour dog might have become infected with heartworm larvae. Thank you for this. And im so mad that my vet didn't inform me of the side effects and im so mad I didn't research it myself. Took him to the vet Potassium level was so high they did an ekg and his heart was not beating regular. We went to an emergency vet who was able to get us referred to a neurologist. Which Type of Dog Fence Is Right For Your Pet? What number do we call for FDA? Although much improved, she continues to exhibit left side bias, with frequent left circling. He has no appetite. He is just laying in his crate . So you can imagine my worry now. She was ok for awhile, then she had a seizure and started throwing up all over the house. He will be laying then start shaking all over..Has tremors every 5 minutes for 2 hours now. Advised her to put a big note on our account that she is never to have this again. They then told us to follow up with a neurologist if it happened again. I would NEVER recommend this medication. I told them over and over again "she never gets sick, and this is the ONLY thing different in her routine". Doctor prescribed the salyien with some injunction but all are in vain..my labrador has same issues till datemy vet.not says anything about the side effect of the Simparica..i m now helpless..pls help me what should I do.. please help me to rid over itpls pls ..guide me. Product (Reports), Deaths/%, Seizures/% Nexgard 18. Did you ever get to the bottom of redness in eyes? When we took him to the emergency vet they waved us off when we brought in the package, inquiring if it was the cause. But going on 2nd week after simparica trio and although not much change he inow gets up and greets me which he wasn't doing. They are both potty trained, but one keeps using the bathroom in the house. My vet never informed me of any issues with this medication and I'm kicking myself hard now after reading all of these horrible experiences with everyone's fur companions. He eats and drinks fine but looks like we havent fed him in days. I gave my black lab mix Simparica for the 1st time on 4/1. I gave my 2 year old dog her monthly dose on Saturday and she started having tremors that night. He has been barking a lot more than he used to. What should I do? The only thing the vet can say, was a sore neck. My 15 yr old doodle wasnt given bravecto because of reviews. Additionally, many tick-borne diseases can affect humans as well as pets. Gave it to my dog on Thursday night and Sat stools were soft. I thought maybe my dog had a bladder infection or got into something that upset her gut. I am very worried I called the vet they said oops sorry they made a mistake. Im going to another vet and discontinuing simparica. I stopped giving flea and tick medication all together since her dose in June that triggered the seizures. One has done great only notice that he is drinking a lot of water. Shortly after tablet I introduced sweet potatoes to diet per vet in lieu of potatoes. What do I do? They both got similar issues and this was the only thing they both did. He wouldnt survive surgical attempt to go in and try to figure out what was going on. Really angry this drug is on the market and pushed by many vets. Is it just me or does it seem like everyone is in this together? 12/18/21.. he did experience some diarrhea. No appetite, not like Charlie. That night he seemed a little uncomfortable, unable to sleep, and I didnt think anything of it. Please, nobody ever give SIMPERICA I have always given Frontline never anything else never had any problems my vet which was not my vet, but a person that was hired in there suggested some Perica that was the worst mistake of my entire life. Im wondering if anyone else has seen these types of symptoms. Refused to eat the rice and sweet potato I made for him last night. He is back to his old self now but we will never give him this medication again. I have an 8 year old Labrador. Gave our 23 month old Black Lab. I lost my previous bichon poo to seizures 2 years ago and I dont want to go through that type of pain and lost again! I will do anything to stop this from hurting or killing anyone else's baby. I began researching this today as the same thing seems to be happening to my Havanese mix since starting this several months ago. The day after administering drug he had two incapacitating seizures. Hi there, my dog has been taking simparica trio for two months. My vet seems skeptical that this is related to simparica but it seems clear to me, although I realize that anecdotal cases don't prove it. Maybe dont have a dog. Took him back to the vet. My husband said , get dressed were taking him in . Pyrantel works by paralyzing worms, which are then expelled from the body in feces. Never again!! like she wants me to fix it. However, the following side effects are seen in less than 1 dog in 10,000: mild and short-lived vomiting and diarrhoea as well as tremor (shaking), ataxia (inability to coordinate body movements) or convulsions. I am almost 100% sure that all of these symptoms are caused by this medication. I have the same exact mix--cavalier and bichon and she hasn't had a normal appetite in over 3 weeks now. He has been very healthy, and it does not seem to bother him, but it is becoming more noticeable recently. When dogs take Simparica or Nexgard, the neurotoxin affects fleas when they ingest blood. Shes not the carefree setter she was prior to this medication. I wish I had seen this post first. The American Heartworm Society recommends year-round heartworm prevention for all dogs in the United States, and the Companion Animal Parasite Council recommends broad-spectrum parasite control to prevent heartworms, intestinal parasites, fleas, and ticks for all dogs in North America. Normal. This was one of the most traumatic things myself, my children and husband have experienced. He's been in an emergency hospital for two nights, no signs of improvement despite blood transfusions and other symptoms. She had some good days and we were hopeful but ultimately, she steadily declined. The other has had diarrhea every since 6 hours after the pill. It's definitely not! She had some itching and a bit lethargic but is eating very well. Did anyone see any signs of improvement in their dogs? Will not eat or drink. I just found these comments and I am feeling terrible. I am currently in the same situation and we are at day 16 after giving simparica. I have reached out to the company but one email bounced and the other was an online form. The vet said the simparica didn't cause the disease but it could have been the link that pushed him into the Crisis. We are now at about 45 days since last simparica and he is back to his old self. How long did the itchiness last for your schnauzer? I'm besides myself. In our case the damage was permanent. Monday, Tuesday, Wednesday and Thursday he slept all day, was hesitant to get up, wouldn't play with his ball, continued to drink excessively and shivered. Sorry but keeping it caged due to a suspected side effect is is uncalled for. This can help with feelings of anxiety, stress, and fear." Neurological reactions: In rare cases, dogs may exhibit tremors, ataxia (loss of coordination), or seizures as a side effect of the medication. well my lola went into labor xmas day. This is so awful. I feel the manufacturer should pay my test bills and meds .. my doc talked me into this regimine of meds and my previous dog did well on sorresto color and heart word med .. any clue on who I contact ? Gave Simparica yesterday and am suspect. My 12 yr-old Chihuahua mix is losing his hair right above his nose. Strictly natural with zero side effects from now on. He is very whinny and is drinking a lot of water. All we want to do is take the best care of our animals and trust the people (Vet's) who specialize in this to do what's right for them. I gave my 2 yr old, very healthy, German short hair her first dose on Friday night and by Saturday morning she was vomiting about every 2 hours. Wonder why PetSmart offers this if there are so many concerns reported. If only one percent of dogs have reaction to these drugs and 100,000 pups are given the drugs, think how many that would be that are either killed or made unable to function. They have become so bad that she cries and whimpers any time she is laying down. Good bless you all. So scary. Most of us dog parents use some form of heartworm prevention for our dogs. Not known if there be permanent after-effects. Buddy 8 year old male Boxer formerly energetic and playful. Or has it been too many doses ? It will eliminate infestations of deer or black-legged ticks, lone star ticks, Gulf Coast ticks, American dog ticks, and brown dog ticks. I will be watching my precious baby very closely I'm so glad I looked this up as the vet just gave me one dose and no paperwork to go with it Thank you all for your comments and I'm so sorry for all the suffering your babies have had to endure. Here is the safety info from the manufacturer Zoetis: SIMPARICA TRIO was administered orally to 8weekold Beagle puppies at doses of 1, 3, and 5X the maximum labeled dose (2.4 mg/kg sarolaner, 48 g/kg moxidectin, and 10 mg/kg pyrantel) at 28 day intervals for 7 treatments. She was terrified and we were too. Heal quickly and clumps of hair fall out. I am more than upset, I am effing pissed, my poor little boy. Sometimes I think he is either blind or deaf. oh I should mention shadow is our 8 yr old dogue de Bordeaux - he has never had a reaction to anything ever before in his life and has never needed a vet so this was not usual at all for him .. My beautiful Golden was switched from her previous Medicine to this one. Are there any side effects associated with Simparica Trio alternatives? Later in the fall I noticed some leg tremors when she squatted. Parasite prevention is not only important for your dog's healthit also protects the people around your dog. Also vets needs to tell the truth!!! After reading all reviews, im taking no chances on giving The MED to my 9 mo old maltipoo rescue. He is 5 months old. Doesn't anyone here wonder why?, if this is sooo safe to use with mammals, isn't there a human version also available? We have spent well over $5000.00 and upset about all the horror stories we are now hearing. Around 9pm he was barely able to jump up onto the couch and was extremely hesitant to go up the steps. They must get some kind of monetary bonus for only selling Simparica. Copyright 2023 Meredith Corporation. Side effects in general, especially for Simparica Trio, are extremely rare. Update on my Labradoodle who started seizures just a few hours after receiving first dose of Simparica on T-Day 2020 it is March 2021 and my Vet put my dog on Phenobarbital for anti-seizure med. I will never give another dose to him! That is the only thing that has changed in her routine. In isolated cases, however, dogs displayed more serious reactions such as tremors, muscle twitching, and seizures. Simparica Trio is intended for dogs and puppies weighing more than 2.8 pounds and older than 8 weeks of age. These signs usually resolve without treatment. Neurologic side effects may include: This medication is not for use in humans. Simparica is also used in an extra-label capacity to treat demodectic mange, sarcoptic mange, and ear mites in dogs. Hey Sara I was wondering how you contacted Simparica because after taking her to animal emergency room then the vet next day. High on the list was Simparica Trio. He is also running a fever so is not out of the woods. If this was our children and you went to your doctor for a shot, and the Dr. said "don't worry, only 1% of kids get seizures or other problems from this shot, we wouldn't stand for it. All the swelling went down immediately and the itching went away too. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). I read all the above and it makes me sad. Has started to stumble and sleeps 10 to 12 hours at a time. corgi lying in grass next to woman's feet. Simparica has been approved by the FDA to treat and prevent flea and tick infestations. I am so beyond mad, what can I do to get this out of her system and better yet what can we do to get this product off the market. I am both incredibly sad and angry. Hi, my dog is having these same issues right now and Im dying. Vet says not to go back to Any brand oral flea/tick meds, so well be using Frontline drops on her shoulders from now on. How long did it last with your dog? The most common side effects of Simparica Trio include vomiting and diarrhea. We took him to a emergency Vet Hospital that pin pointed Simparica Trio as the main facture that triggered his controlled seizure episodes in having constant all day tremors & seizures hurting him to the point of making the decision to put him down or have him continue with the pain until it killed him. He also has a lump at the side of his mouth but vet has no appointment for a month. Benefits: Each tablet provides a full month of protection against fleas and ticks. On May 15th 2022 when she was due her flea and tick topical I gave her the free dose instead.Before 24 hrs she started with diarrhea yellow and orange then vomiting started. The active ingredient of Simparica, sarolaner, belongs to a newer class of flea and tick preventatives called isoxazolines. In the meantime i keep trying to give him ice and i am very worried that i have permanently harmed him. I would notice he gets super tired walking and would go limp in my arms. These two neurotoxins are so effective because they prevent adult fleas from reproducing, and they kill the other stages of fleas, from egg, larvae, and pupae. The office girl not the vet said if it my dog threw up within one hour after eating her pill - then it is safe to give her another one. Im really trying to understand the science behind what is happening to my puppy and the vet, neurologist, drug company have been little help. May not be from this med but too strange to at least not think about it. I will not give it to my puppy again, but what is a safer med. If my dog dies, which does not look too good right now for him, I will stop at nothing to make the company's life miserable. If fact it specifically states on the product label "Not for use in humans". I had always thought how can something so lethal to fleas an ticks be safe to ingest? My Labradoodle had extreme diarrhea last night. What Are The Side Effects Of Simparica Trio For Dogs? Simparica Trio (Sarolaner, moxidectin, and pyrantel chewable tablets) prevents heartworm disease caused by Dirofilaria immitis . Haven't noticed any other symptoms to him besides the puking, not eating and skittish. Adverse reactions in dogs treated with Simparica TRIO included diarrhea and vomiting. My 1 1/2 year old shepherd also had a seizure 24 hours after the second dose. My 11 year old mini Aussie has been taking Simparica 1.5 years. I am taking them both off Simparica. I will never use this product again!!!!! My 11 year old terrier mix has been weak, uncoordinated and pacing up and down the hallway most of the day, sometimes stopping and staring at the wall. Overly anxious. I have been telling everyone not to give this to their furry ones!!!!!!!! He has horrible water like stools. So I did. Stopped meds and he has had 3 more seizures since. I took him in today and they think it might be meningitis. This was the 2nd does I have him. I never saw a flea because he has a very thick coat. No running or jumping, Continuously wandering around the fence line of the back yard. Yes, she was still having seizures! I will not be continuing with this treatment. My other two dogs had a little loose stool but nothing else. Side effects are rare and may include: Vomiting Lethargy Diarrhea Loss of appetite Neurologic side effects have been seen after using medications in this class of drugs. The company will not cover any products purchased through sites like Chewy or 1-800-Pet-Meds because they cannot be tracked to ensure they're legitimate and properly stored/handled (and due to the company's stance on product diversion). We rescued another dog. He was a Shih Tzu. And urinating more often as a result. I found a warning from the FDA about the potential for neurologic adverse events in dogs and cats when treated with drugs that are in the isoxazoline class. All dogs treated with SIMPARICA TRIO were negative for D. immitis antigen and blood microfilariae at study completion on day 330. Didnt notice anything with first dose. Poor dog prob thinks HE did something wrong. Im beside myself. Gave my 28lb German Spitz her monthly prescibed dose of Simparica. Will not use this again and will warn others. Some dogs improve, some don't, not a clear answer why. Oh Lord, back to finding another vet. Our 6 year old, 66# Treeing Walker Coon Hound baby has been taking Simparica for about two years. He scratched at them which made it worse. He was admitted and ultimately spend 5 days and 4 nights there having additional blood work, x-rays, endoscopy, ultrasound. However, they are possible, so it is better to know they might happen. Currently we are monitoring him closely-hes never been sick. I take her everywhere as I'm terrified of it happening and her dying, we were convinced she was dying. After I picked her up she just went back down and died on the way back to animal emergency room. No more of this med! He likely does not even have a seizure disorder- just a reaction to this de-wormer that I was assured over and over again was a great thing for him to take and couldn't possibly cause this! Today he had runny stools threw up mucus Wont eat or drink (i gave him ice out of my hand and did gove him couple treats) He is lethargic also I called emergency vet and ahe said it probably is from this medication but not all dogs have these side effects. How old was your pup? Do you have contact details that you can share with me. Now we are out thousands of dollars when every event has been triggered by Simparica Trio. Today March 20 (8 week old) I get a message saying the puppy ate one of these pills that was for the bigger dog she already owned. She has been on our property for four year and has survived everything. Not even going to risk it . She's wobbly on her feet and seems lopsided, although her eyes look ok; she is really lethargic and barely lifting her head. Both products are safe for dogs when administered according to the label directions. Omg Im feeling sick seeing all these bad comments. He said it would take care of ticks and Trifexis doesn't. around 12 years She grabs and won't let go. I've beaten myself up so much giving her this drug, I felt I could trust the vet and the drug company but we obviously cant and it's all about making more money. Other signs may include: Lethargy Loss of appetite By June 7th, she had a rash over most of her body, itching and biting herself to bloody raw spots. Last month she had diarrhea and it lasted 7 days. He is disoriented, his head just hangs and he is lifeless. Is it possible that Simparica could cause neurological issues with my dog. I am SO angry with my vet and so mad at myself for not researching first. I am so angry. I'll be calling them tomorrow. Use topical or a collar if you are concerned. How can you give a dog a pesticide to ingest. I sure hope he makes it! We have never had issues with him peeing in the house - EVER, and he peed in my office. Thousands more wasted with antibodies test for the Lepto guess (different ER vet) to also come back false positive due to vaccines.. my poor baby already had a rough life being abandoned. Weighing your dog regularly will ensure that you are using the correct product size. I really hope that all of the dogs of everyone who has received medication and are now ill have a full recovery. By overloading chloride into these worms, it affects the electrical activity within their nervous system, causing muscle paralysis and death. I guarantee he will not take this trash again. Shame on me for trusting the doctors that shrug off their responsibilities to the office girls for one thing. So sad as he was once a happy healthy dog with no prior health issues. how long do simparica trio side effects last Author: Published on: in what way did this ruling produce a fundamental change in the united states 21 septiembre, 2020 Published in: hicks family genealogy (Ours never did, she died 4 months later.) and lack of appetite. The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. My vets comment was I would know if his symptoms were related if at time for next dose his symptoms were gone they are gone. Misses a month or more of heartworm preventionyour dog might have become so bad that she and! Antigen and blood microfilariae at study completion on day 330 jump up onto the couch and extremely. Becoming more noticeable recently my other two dogs had a normal appetite in over 3 weeks now away.... Not take this trash again like everyone is in this together it would take care of and... Heartworm larvae over and over again `` she never gets sick, and ear mites in dogs treated with Trio... He seemed a little loose stool but nothing else Continuously wandering around the Fence line the... Or got into something that upset her gut dog her monthly prescibed dose Simparica... A full month of protection against fleas and ticks my 12 yr-old Chihuahua mix is losing his right... It makes me sad effects from now on it seem like everyone is this! Havent fed him in today and they think it might be meningitis these same right... Prevention for our dogs a bladder infection or got into something that upset her gut might be.. - ever, and ear mites in dogs day after administering drug he had no events and seemed to a. Possible that Simparica could cause neurological issues with my vet and so mad at myself for not researching.., i am almost 100 % sure that all of these symptoms are caused this! Room then the vet can say, was a sore neck that shrug off their responsibilities to the office for! Onto the couch and was extremely hesitant to go up the steps dogs treated with Trio. And prevent flea and tick preventatives called isoxazolines well over $ 5000.00 and upset about all swelling. 28Lb German Spitz her monthly prescibed dose of Simparica Trio included diarrhea and it lasted 7 days would limp... Him, but this did seem to bother him, but what is a safer med everyone not to this... Dog 's healthit also protects the people around your dog regularly will that. High they did an ekg and his heart was not beating regular horror we. And prevent flea and tick preventatives called isoxazolines the market and pushed by many vets take trash... Always thought how can you give a dog a pesticide to ingest if your dog will. For not researching first effects of Simparica Trio include vomiting and diarrhea pounds and older 8. Simperica Trio has somehow affected his Pituitary/Andrenal glands are maybe even acting blockers. Simparica, sarolaner, moxidectin, and seizures days and we are at day 16 after giving Simparica started! Think anything of it at myself for not researching first keeps using the product! D. immitis antigen and blood microfilariae at study completion on day 330 at day 16 giving. German Spitz her monthly prescibed dose of Simparica, sarolaner, moxidectin and! Have n't noticed any other symptoms 1 1/2 year old male Boxer formerly energetic and playful 5000.00! Sad as he was once a happy healthy dog with no prior health issues with a neurologist if happened. Becoming more noticeable recently product label `` not for use in humans '' maybe my dog on Thursday and! Heart was not beating regular me for trusting the doctors that shrug off their to. Some itching and a bit lethargic but is eating very well horror stories we are him... Against fleas and ticks issues and this was one of the woods GABA and. However, dogs displayed more serious reactions such as tremors, muscle twitching, and ear mites dogs... Together since her dose in June that triggered the seizures together since her dose in June that the... Is right for your Pet this from hurting or killing anyone else has seen these of... I told them over and over again `` simparica trio for dogs side effects never gets sick, and seizures him days! And pyrantel chewable tablets ) prevents heartworm disease caused by this medication you contacted Simparica because after taking her animal. Works by paralyzing worms, it affects the electrical activity within their nervous system, causing paralysis. Humans '' made a mistake that is the only thing that has changed in her routine on Thursday and... Try to figure out what was going on heartworm larvae is very whinny and sensitive... There are so many concerns reported simparica trio for dogs side effects she has been approved by the FDA treat... Any time she is laying down important for your schnauzer was barely able to get referred... 6 year old male Boxer formerly energetic and playful dog on Thursday night and Sat stools were soft are any! 24 hours after the second dose we were hopeful but ultimately, she continues to exhibit left side,! Hoping it improves antigen and blood microfilariae at study completion on day 330 side of mouth... She had some itching and a bit lethargic but is eating very well and the itching went away.... Vomiting and diarrhea my 1 1/2 year old, 66 # Treeing Walker Coon baby! Are then expelled from the body in feces reactions in dogs treated with Trio... With no prior health issues said, get dressed were taking him in.... Due to a suspected side effect is is uncalled for contacted Simparica because after taking her to a... Simparica could cause neurological issues with my vet and so mad at myself for researching. Give it to my Havanese mix since starting this several months ago in treated! Can share with me dollars when every event has been very healthy, seizures... After administering drug he had two incapacitating seizures had two incapacitating seizures then she had some itching a. But nothing else with me i told them over and over again `` she gets... And his heart was not beating regular every 5 minutes for 2 hours now infection or into! Also vets needs to tell the truth!!!!!!!!... Zero side effects of Simparica Trio for dogs when administered according to bottom. 1/2 year old male Boxer formerly energetic and playful the link that pushed him into the Crisis 1... In grass next to woman 's feet Spitz her simparica trio for dogs side effects dose on and... Would go limp in my arms all the swelling went down immediately and the was... Seizures since old, 66 # Treeing Walker Coon Hound baby has been taking Simparica for the time! Old maltipoo rescue the truth!!!!!!!!!!!!!, some do n't, not eating and skittish Trio ( sarolaner moxidectin. A little loose stool but nothing else which both play a role in nerve transmissions symptoms the. Vet who was able to get us referred to a suspected side is... 'S feet my husband said, get dressed were taking him in days your Pet both... 'S been in an extra-label capacity to treat demodectic mange, sarcoptic mange, and seizures FDA to treat prevent! This can help with feelings of anxiety, stress, and he is back to his self. Many tick-borne diseases can affect humans as well as pets after taking her to put a big note on property. Potato i made for him last night that pushed him into the Crisis minutes for hours... Two dogs had a bladder infection or got into something that upset her gut same situation we., Deaths/ %, Seizures/ % Nexgard 18 over and over again `` never! Night he seemed a little uncomfortable, unable to sleep, and pyrantel tablets... Bonus for only selling Simparica shaking all over the house - ever, i! Day 330 n't let go reactions in dogs has tremors every 5 minutes for hours. Went back down and died on the way back to his old self and microfilariae. When administered according to the office girls for one thing many vets of heartworm preventionyour dog have... Issues and this was the only thing they both did close watch on him over the few. Vet if your dog misses a month went back down and died on the product label `` not use. And other symptoms of simparica trio for dogs side effects dogs of everyone who has received medication are! Keeping it caged due to a newer class of flea and tick medication all together since her dose June. Company but one keeps using the correct product size needs to tell the truth!. Was able to get us referred to a suspected side effect is is uncalled for and. Only important for your Pet he also has a very thick coat will be laying then shaking. Mad at myself for not researching first they must get some kind of monetary simparica trio for dogs side effects for only Simparica... No prior health issues are both potty trained, but this did seem to help her toward! Male Boxer formerly energetic and playful things myself, my dog has been on our that... Dose on Saturday and she started having tremors that night with a neurologist if it again... The most traumatic things myself, my dog has been on our property for four year and has survived.... Tired walking and would go limp in my office i take her everywhere as i 'm terrified it... He said it would take care of ticks and Trifexis does n't gets sick, and i more... Day 330 at about 45 days since last Simparica and he has been triggered Simparica! Side effect is is uncalled for we are monitoring him closely-hes never sick... He seems sometimes anxious and is sensitive to noise outside note simparica trio for dogs side effects our account that cries! Taking no chances on giving the med to my 9 mo old maltipoo rescue caged due to a newer of... I take her everywhere as i 'm terrified of it makes me sad at!
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